Kulim Kht BioNavis QCMD - advance surface and interface analysis

 We are excited to announce the launch of the BioNavis QCMD instrument range!

The Quartz Crystal Microbalance with Dissipation (QCMD) instruments complement our existing MP-SPR instruments, completing our suite of real-time and label-free analytical tools.

BioNavis QCMD is designed to advance surface and interface analysis with high precision measurement of key parameters, including viscoelasticity and bound mass. Key benefits include:

High Sensitivity and Accuracy:

Detect even the smallest changes with high-frequency sensors, ensuring you get the most reliable data for your research.

Versatile Applications:

Ideal for a wide range of applications, including biomolecular interactions, material science, and sensor development.

User-Friendly Interface:

Easy-to-use QuickLock cells, sensors, and intuitive software, making complex analyses simpler and faster.

Stay tuned upcoming webinars to learn how our innovative solutions can benefit your research. For more information,

https://bionavis.com/technology/qcmd/

SPR Multi Parameter Bionavis Kulim Hi-Tech

 

Corrosion High Pressure High Temperature RCE Autoclave Cortest + Kulim Hi Tech Sdn Bhd

 

HPHT Autoclaves 

Cortest autoclave systems are used for high pressure and high (and low) temperature (HPHT) test applications including: corrosion testing, electrochemical studies, corrosion inhibitor analysis, shear stress analysis, slow strain rate testing

Above image shown HPHT RCE autoclave.

Inhibitors Studies Bubble Tests- Gill 6,8,12 ACM Instruments - Kulim Kht

Typical results are shown as metal has the highest corrosion rate but on the addition of the inhibitor the rate drops to the lowest. The test should be repeated at least three times and the results compared for scatter. The percentage protection of an inhibitor is usually quoted this is defined as 100*(uninhibited rate-inhibited rate)/uninhibited rate. The bubble test software will display this for all channels under test. The temperature of the test is important as a whole set of percentage protection values is displayed with respect to temperature.

Bubble Test facilitates running tests in multiples; tests are set up using a simple Bubble Wizard, a series of LPR tests are collected over time giving Corrosion Rate results. Results can be printed at the end in many ways including tables, lines and bar graphs. Cells (or Channels) are assigned together into Groups, each group has an Add Inhibitor button, once pressed, end corrosion rates can be calculated at the end of the test over 3 periods – prior to Add Inhibitor, after 2 hours and after 16 hours, this enables Percentage Protection to be calculated.

Bubble Test - LPR - Inhibitors Gill 6,8,12 ACM Instruments Kulim Kht

Testing of these chemicals is performed by makers and users. Makers set up initial screening to not reject any potential good ones. Users set up initial screening to reject any potential bad ones. Test metal should be the same metal as that to be protected as should be the test fluid. The two most widely used tests are LPR and Tafel plots. Both are ideally performed using a Gill 8 or Gill 12. The use of a multiple channel instrument allows for replication to gain confidence in the results. The Bubble Test software automatically groups the tests and prints inhibition reports using the LPR method. After all the small LPR perturbations have been made an optional Tafel sweep is performed to obtain the Tafel slopes. AC impedance is less commonly used except with high resistance electrolytes where the IR drop in the solution needs to be measured and overcome. 

Potentiostat KHT ACM MultiPot 16.

The Pot 16 has 16 potentiostats built in, each at a fixed range i.e. not changed through the software. This allows very long tests of electrodes under potentiostatic control to be performed in complete certainty that the set potential will not be changed. Current and potential are recorded with time. Ideal for the study of cathodic disbondment. For more information click here.

Surface Plasmon Resonance (SPR) Kulim Kht Bionavis Kinetics Titration

Introduction

Surface Plasmon Resonance (SPR) is a popular real-time label-free method to assess biomolecular interactions especially in the fields of drug discovery and biosensor development. Multi-Parametric Surface Plasmon Resonance (MP-SPR) scans a broad angular range and records whole SPR curve. Hence from the same measurement, MP-SPR provides more information about changes at the surface than traditional SPR. Additionally, MP-SPR records also bulk (solvent) effect simultaneously with the binding signal in every channel. Thanks to the PureKinetics™ feature, bulk effect can be separated from molecular binding events in real-time, providing more reliable results and enabling measurements, which are not possible using traditional SPR instruments. PureKinetics™ enables measurement of kinetics in altering dissociation buffers (Application Note #147) To quantify affinity and kinetic parameters of the biomolecular interaction, binding at not less than two concentrations of the analyte needs to be measured. Concentrations need to be in the range close to the dissociation constant (KD), and usually a few more concentrations are required, as affinity is typically unknown. Conventionally, the dissociation rate is measured after each analyte concentration. Additionally, if dissociation is slow, the remaining part of the bound analyte is removed using a run of regeneration solution between the sample injections. Ideal regeneration breaks the bonds between the ligand and the analyte without deactivating the molecules on the surface. However, such regeneration is sometimes difficult to achieve and also the ligand is damaged. The KineticTitration option allows the injection of samples sequentially and the dissociation is measured only at the end of the whole run. This shortens the time required for the whole measurement cycle (Figure 1). KineticTitration is especially useful when: • results are needed quickly • there is less time available for assay optimization (such as for finding a suitable regeneration solution) • surface is difficult or impossible to regenerate without losing the activity of the ligan