Kulim Kht Nanoparticle with MPSPR BioNavis

Gold nanoparticles were immobilized on a monolayer selfassembled
on gold. Functional groups on the chain ends of the
monolayer facilitated an anchoring of gold nanoparticles to the
layer. Multi-Parametric Surface Plasmon Resonance (MP-SPR)
enabled a real-time measurement of the binding of the gold
nanoparticles to the surface layer.
Introduction
Gold nanoparticles (AuNPs) exhibits interesting optical and electronic
properties that find application in sensors, catalysis, electronics,
photonics, solar cells, cancer diagnosis and therapy. Controlled attachment
of Au nanoparticles at a solid interface is required for many of
these applications. Although many methods have been developed to
fabricate Au nanoparticle assemblies, developing simple and effective
routes is still very attractive. Usually, the immobilization can be
performed using a covalent or an electrostatic interaction between
the nanoparticles and the substrate. In this study functional molecules
are used for linking gold nanoparticles to a solid surface. Molecules
possessing functional groups can be attached to the solid surface in
a controlled manner and permits nanoparticle immobilization.

Conclusions
Monolayers with functional groups assembled on a gold surface
can be used for coupling of gold nanoparticles. In this study MP-SPR
turned out to be a unique method for determining the deposition of
metal nanoparticles to the surface layer in real-time. AuNPs exhibit
strong surface plasmon resonances and even a large response could
be observed by MP-SPR when nanoparticles were interacting with
the surface layer. Functional groups on the chains ends enable
an anchoring of gold nanoparticles or even embedding into the
chains. MP-SPR is a unique tool for studying metal nanoparticles for
applications in sensors, electronics, photonics, solar cells or cancer
diagnosis and therapy.